In the last decade in Europe and North America the first place among malignant tumors of the digestive tract is colon cancer, which accounts for more than 50% of cancers of the gastrointestinal tract.
In consequence of the aging world population is expected deterioration in the future. Celebrated worldwide increase in the incidence of cancer of the rectum, he was the most pronounced in developed countries.
Scientists estimate over the lives of more than 4-6% of the population develops colon cancer.
At the moment proved is the following sequence of events:
- Adenomatous polyp;
- Adenomatous polyp with dysplasia;
- A cancer in the polyp;
- A common cancer.
These stages of development of carcinoma of the colon and rectum take several years.
The above stages of development suggest that the precancerous diseases of the rectum should be primarily attributed polyps. Colon cancer in most cases it develops from polyps. Considered premalignant adenomatous polyps, diffuse polyposis and ulcerative colitis.
Polyps are growths of the epithelium in the form of small papillae or circular formations, towering above the surface of the mucosa. Preventing colon cancer is to identify and remove precancerous polyps and cancerous tumors and most curable stage in its development.
This prevention is proven effective and is recommended for persons belonging to the groups of moderate and high risk.
There are several methods for diagnosis of early stages of cancer, including fecal occult blood test and sigmoidoscopy and colonoscopy (using a flexible light).
The most effective method for early detection of polyps and colon cancer is colonoscopy. It is believed that the preventive value in relation to colon cancer has a fiber-rich diet. Primary prevention of colon cancer is reduced to a balanced diet to include foods that contain a sufficient amount of dietary fiber of fruits and vegetables rich in vitamins A and C.
Early endoscopic diagnosis and removal of colon polyps - the key to successful prevention of cancer!
Celecoxib inhibits the development of colon cancer and prevents the development of prostate cancer.
Nevertheless, prevention of colon cancer is considered as the most important "target" for the preventive use of celecoxib, since this is the area accumulated the largest number of evidence of their effectiveness. Obvious choice of drugs for the prevention of cancer, is a selective COX-2 inhibitors (Celecoxib).
The most interesting of these celecoxib, which has the highest level of gastrointestinal safety. Celecoxib capsule has a mechanism for suppression of tumor cell growth associated with the blockade of cell cycle and suppression of DNA synthesis.
It is interesting that a number of pharmacological effects, which determine the antiproliferative effect of celecoxib and proapoptoznoe may be specific to this drug.
Decrease the risk of tumors in mice receiving Celebrex for over a year was about 31%.
So far celecoxib appears to be very interesting and promising drug with a multifaceted mechanism of therapeutic effects and possible point of application in various fields of modern medicine. Pill AZ pharmacy the way you can buy celecoxib easily.
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